2994634-52-3
2994634-52-3
Chemical Structure
CES2-IN-1
- CAS No.: 2994634-52-3
- Formula:C16H11ClN4
- Molecular Weight:294.74
InChIKey: GMVGUDXEJRDGED-UHFFFAOYSA-N
SMILES: ClC1=CC=CC2=C1N=C(C=C2)NC3=NC4=CC=CC=C4N3
Biological Activity: CES2-IN-1 (Compound 24) is a reversible and selective CES2 inhibitor (IC50: 6.72 μM for human CES2). CES2-IN-1 reduces the level of CES2 in living cells. CES2-IN-1 is effective against Irinotecan (HY-16562)-induced delayed diarrhea and DSS-induced ulcerative colitis[1].
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CES2-IN-1 | 99.93% | CES2-IN-1 (Compound 24) is a reversible and selective CES2 inhibitor (IC50: 6.72 μM for human CES2). CES2-IN-1 reduces the level of CES2 in living cells. CES2-IN-1 is effective against Irinotecan (HY-16562)-induced delayed diarrhea and DSS-induced ulcerative colitis. | ||||||||||||||||||||
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