2998941-15-2
2998941-15-2
Chemical Structure
JNK2-IN-1
- CAS No.: 2998941-15-2
- Formula:C30H26N4O5
- Molecular Weight:522.55
InChIKey: RHGFVWDZWMEFNR-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)N2C(C=C(C(C(NC3=CC=C(OC4=C5C(C=C(C(OC)=C5)OC)=NC=C4)C=C3)=O)=N2)C)=O
Biological Activity: JNK2-IN-1 (Compound J27) is a JNK2 inhibitor (Kds: 79.2 μM). JNK2-IN-1 has anti-inflammatory activity. JNK2-IN-1 decreases the release of TNF-α and IL-6 through inhibiting the activation of NF-κB/MAPK pathway. JNK2-IN-1 alleviates the symptoms of LPS-induced acute lung injury (ALI) and sepsis[1].
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JNK2-IN-1 | JNK2-IN-1 (Compound J27) is a JNK2 inhibitor (Kds: 79.2 μM). JNK2-IN-1 has anti-inflammatory activity. JNK2-IN-1 decreases the release of TNF-α and IL-6 through inhibiting the activation of NF-κB/MAPK pathway. JNK2-IN-1 alleviates the symptoms of LPS-induced acute lung injury (ALI) and sepsis. | |||||||||||||||||||||
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