2998942-88-2
2998942-88-2
Chemical Structure
HDAC6-IN-18
- CAS No.: 2998942-88-2
- Formula:C16H13N3O7S
- Molecular Weight:391.36
InChIKey: CKHUIFFTCIFDOH-UHFFFAOYSA-N
SMILES: [O-][N+]1=C(C(OCC2=CC=C(C=C2)C(NO)=O)=NO1)S(=O)(C3=CC=CC=C3)=O
Biological Activity: HDAC6-IN-18 (Compound 4) is a first irreversible HDAC6 isoform selective inhibitor with potent anti-multiple myeloma activity. HDAC6-IN-18 has HDAC6 inhibitory activity in RPMI8266, U266 and MM.1S cells with IC50 values of 0.17, 0.7 and 0.42 μM, respectively[1].
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HDAC6-IN-18 | HDAC6-IN-18 (Compound 4) is a first irreversible HDAC6 isoform selective inhibitor with potent anti-multiple myeloma activity. HDAC6-IN-18 has HDAC6 inhibitory activity in RPMI8266, U266 and MM.1S cells with IC50 values of 0.17, 0.7 and 0.42 μM, respectively. | |||||||||||||||||||||
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