3003026-16-9
3003026-16-9
Chemical Structure
HPK1-IN-31
- CAS No.: 3003026-16-9
- Formula:C30H33N7O3
- Molecular Weight:539.63
IUPAC Name: (S)-35-(1-(2-hydroxy-2-methylpropyl)-1H-pyrazol-4-yl)-5-(hydroxymethyl)-7-oxa-2,4-diaza-3(2,4)-pyrimidina-1(1,3),6(1,2)-dibenzenacycloundecaphane-14-carbonitrile
InChIKey: DSSNAGYVGTYAGH-AREMUKBSSA-N
SMILES: CC(O)(CN1C=C(C=N1)C2=CN=C3N=C2N[C@@H](C4=C(OCCCCC5=CC(N3)=CC=C5C#N)C=CC=C4)CO)C
Biological Activity: HPK1-IN-31 (compound 5i) is an orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 value of 0.8 nM. HPK1-IN-31 has anti-tumour activity and has great potential for immunoresearch[1].
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HPK1-IN-31 | HPK1-IN-31 (compound 5i) is an orally active hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 value of 0.8 nM. HPK1-IN-31 has anti-tumour activity and has great potential for immunoresearch. | |||||||||||||||||||||
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