3004676-87-0
3004676-87-0
Chemical Structure
FXR/CES2 modulator 1
- CAS No.: 3004676-87-0
- Formula:C27H21Cl2NO5
- Molecular Weight:510.37
SMILES: O=C(O)COC1=CC=C(C2=CC=C(OCC3=C(C4CC4)ON=C3C5=C(Cl)C=CC=C5Cl)C=C2)C=C1
Biological Activity: FXR/CES2 modulator 1 (compound LE-77) is a doul modulator that activates FXR and inhibits CES2. FXR/CES2 modulator 1 effectively mitigates the intestinal toxicity of irinotecan[1].
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FXR/CES2 modulator 1 | FXR/CES2 modulator 1 (compound LE-77) is a doul modulator that activates FXR and inhibits CES2. FXR/CES2 modulator 1 effectively mitigates the intestinal toxicity of irinotecan. | |||||||||||||||||||||
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