3004884-16-3
Chemical Structure
AXIN2/β-catenin-IN-1
- CAS No.: 3004884-16-3
- Formula:C14H8F5NO2S
- Molecular Weight:349.28
InChIKey: KBDPWTNIEHFUGC-UHFFFAOYSA-N
SMILES: O=S(C1=C(C(F)=C(C(F)=C1F)F)F)(N2CC3=C(C2)C=CC=C3)=O
Biological Activity: Anticancer agent 291 (Compound 2406) is an anti-cancer agent. Anticancer agent 291 interferes with the integrity of the β-tubulin cytoskeleton and inhibits the Wnt/β-catenin signal transduction. Anticancer agent 291 significantly inhibits the invasion, migration and colony formation of tumor cells. Anticancer agent 291 induces the cell cycle of EC-9706 and HT-29 cells to arrest at the G2/M phase and inhibits cell proliferation. Anticancer agent 291 can be used for the study of gastrointestinal cancer[1].
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AXIN2/β-catenin-IN-1 | Anticancer agent 291 (Compound 2406) is an anti-cancer agent. Anticancer agent 291 interferes with the integrity of the β-tubulin cytoskeleton and inhibits the Wnt/β-catenin signal transduction. Anticancer agent 291 significantly inhibits the invasion, migration and colony formation of tumor cells. Anticancer agent 291 induces the cell cycle of EC-9706 and HT-29 cells to arrest at the G2/M phase and inhibits cell proliferation. Anticancer agent 291 can be used for the study of gastrointestinal cancer. | |||||||||||||||||||||
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