3006800-41-2
Chemical Structure
Tubulin polymerization-IN-90
- CAS No.: 3006800-41-2
- Formula:C21H14N4S
- Molecular Weight:354.43
InChIKey: ABHQINRTRGQLGN-UHFFFAOYSA-N
SMILES: C1(C=CC=C2)=C2C=CC=C1C3=CN(N=N3)C4=CC(C5=CC=CS5)=CN=C4
Biological Activity: Tubulin polymerization-IN-90 is a tubulin polymerization inhibitor. Tubulin polymerization-IN-90 disrupts tubulin polymerization by binding to the nocodazole-binding site on β-tubulin. Tubulin polymerization-IN-90 induces the release of extracellular vesicles marked by the tetraspanin CD63. Tubulin polymerization-IN-90 induces the release of IL-8 from cells. Tubulin polymerization-IN-90 reduces the viability of cancer cells. Tubulin polymerization-IN-90 can be used in the research of cancers such as acute T-lymphoblastic leukemia[1].
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Tubulin polymerization-IN-90 | Tubulin polymerization-IN-90 is a tubulin polymerization inhibitor. Tubulin polymerization-IN-90 disrupts tubulin polymerization by binding to the nocodazole-binding site on β-tubulin. Tubulin polymerization-IN-90 induces the release of extracellular vesicles marked by the tetraspanin CD63. Tubulin polymerization-IN-90 induces the release of IL-8 from cells. Tubulin polymerization-IN-90 reduces the viability of cancer cells. Tubulin polymerization-IN-90 can be used in the research of cancers such as acute T-lymphoblastic leukemia. | |||||||||||||||||||||
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