3008612-30-1
3008612-30-1
Chemical Structure
JWZ-7-7-Neg1
- CAS No.: 3008612-30-1
- Formula:C50H58Cl2N12O6S
- Molecular Weight:1026.04
InChIKey: BVXLBDBPQFNJKR-DIPNUNPCSA-N
SMILES: CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@H](CC(NCCCCCCCNC(C4CCN(C5=NC=C(Cl)C(NC6=CC(OC)=C(N(C(C(OCC(NC)=O)=C7)=O)C)C7=C6)=N5)CC4)=O)=O)C8=NN=C(C)N28
Biological Activity: JWZ-7-7-Neg1 is a transcriptional chemical inducers of proximity (TCIP) with negative chemical control. JWZ-7-7-Neg1 reduces the ability to bind to BRD4 or BCL6, so it has less cytotoxicity to DLBCL cells, in compared with JWZ-7-7[1].
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JWZ-7-7-Neg1 | JWZ-7-7-Neg1 is a transcriptional chemical inducers of proximity (TCIP) with negative chemical control. JWZ-7-7-Neg1 reduces the ability to bind to BRD4 or BCL6, so it has less cytotoxicity to DLBCL cells, in compared with JWZ-7-7. | |||||||||||||||||||||
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