3011805-61-8
3011805-61-8
Chemical Structure
FGFR4-IN-17
- CAS No.: 3011805-61-8
- Formula:C29H27F3N4O2
- Molecular Weight:520.55
InChIKey: KWCUYDDWUFSZAY-MHZLTWQESA-N
SMILES: FC1(C2=CC(NC(C3=CC(C#CC4=CN=CC(OC)=C4)=C(C=C3)F)=O)=CC=C2[C@@H](N5CCN(CC5)C)C1)F
Biological Activity: FGFR4-IN-17 (Compound (S)-23) is a piperazinyl diflurindan derivative containing pyridinyl. FGFR4-IN-17 is a FGFR inhibitor with IC50 values of 24.2, 16.1, 78.0, and 68.0 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. FGFR4-IN-17 has antitumor activity[1].
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FGFR4-IN-17 | FGFR4-IN-17 (Compound (S)-23) is a piperazinyl diflurindan derivative containing pyridinyl. FGFR4-IN-17 is a FGFR inhibitor with IC50 values of 24.2, 16.1, 78.0, and 68.0 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. FGFR4-IN-17 has antitumor activity. | |||||||||||||||||||||
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