3012624-88-0
3012624-88-0
Chemical Structure
HSD17B13-IN-105
- CAS No.: 3012624-88-0
- Formula:C15H14F3N3O4
- Molecular Weight:357.28
InChIKey: ULKUCAMLQLQWBV-KNVOCYPGSA-N
SMILES: O=C(N1C[C@@H](C)O[C@@H](C)C1)C2=NOC(C3=CC(F)=C(F)C(O)=C3F)=N2
Biological Activity: HSD17B13-IN-105 (Compound EX.87) is a selective 17β-hydroxysteroid dehydrogenase 13 (17BHSD13) inhibitor with an IC50 value of 0.036 μM, showing high selectivity over 17BHSD4 (with an IC50 value of 31.5 μM). HSD17B13-IN-105 is promising for research of liver diseases such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)[1][2].
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HSD17B13-IN-105 | HSD17B13-IN-105 (Compound EX.87) is a selective 17β-hydroxysteroid dehydrogenase 13 (17BHSD13) inhibitor with an IC50 value of 0.036 μM, showing high selectivity over 17BHSD4 (with an IC50 value of 31.5 μM). HSD17B13-IN-105 is promising for research of liver diseases such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). | |||||||||||||||||||||
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