3013618-83-9
3013618-83-9
Chemical Structure
SGI-1776-amide-C6-acid
- CAS No.: 3013618-83-9
- Formula:C27H32F3N5O4
- Molecular Weight:547.57
InChIKey: AVEYUCVDXZKUIO-UHFFFAOYSA-N
SMILES: OC(CCCCCCC(N(CC1)CCC1CNC2=NN3C(C4=CC(OC(F)(F)F)=CC=C4)=CN=C3C=C2)=O)=O
Biological Activity: SGI-1776-amide-C6-acid (Compound S4) is a Target Protein Ligand-Linker Conjugate that contains a Pim inhibitor (HY-13287) and a PROTAC linker, and can recruit E3 ligase. SMARCA2 Ligand-Linker Conjugate-4 is applicable for the synthesis of PROTAC SGI-1776-VHL-02 (HY-186146)[1].
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SGI-1776-amide-C6-acid | SGI-1776-amide-C6-acid (Compound S4) is a Target Protein Ligand-Linker Conjugate that contains a Pim inhibitor (HY-13287) and a PROTAC linker, and can recruit E3 ligase. SMARCA2 Ligand-Linker Conjugate-4 is applicable for the synthesis of PROTAC SGI-1776-VHL-02 (HY-186146). | |||||||||||||||||||||
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