3017162-04-5
3017162-04-5
Chemical Structure
VEGFR-2/c-Met-IN-2
- CAS No.: 3017162-04-5
- Formula:C22H15ClN4O3S
- Molecular Weight:450.90
InChIKey: USQZQKCOSSCRRL-UHFFFAOYSA-N
SMILES: O=C(NC(NC1=CC=C(Cl)C=C1)=S)C2=CC=C(N3C(NC4=C(C=CC=C4)C3=O)=O)C=C2
Biological Activity: VEGFR-2/c-Met-IN-2 (compound 3e) is a VEGFR-2/c-Met inhibitor, with IC50 values of 83 and 48 nM, respectively. VEGFR-2/c-Met-IN-2 exhibits cytotoxic activity against HCT-116 cell line (IC50: 3.403 µM)[1].
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VEGFR-2/c-Met-IN-2 | VEGFR-2/c-Met-IN-2 (compound 3e) is a VEGFR-2/c-Met inhibitor, with IC50 values of 83 and 48 nM, respectively. VEGFR-2/c-Met-IN-2 exhibits cytotoxic activity against HCT-116 cell line (IC50: 3.403 µM). | |||||||||||||||||||||
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