301820-47-3
301820-47-3
Chemical Structure
Multi-target kinase-IN-7
- CAS No.: 301820-47-3
- Formula:C20H14N2O2S
- Molecular Weight:346.40
SMILES: O=C(/C(N1)=C/C2=CC=C3C=CC=CC3=C2O)N(C4=CC=CC=C4)C1=S
Biological Activity: Multi-target kinase-IN-7 (Compound 1e) is an orally active multi-target kinase inhibitor (IC50 values: CDK2=0.314 μM, EGFR=0.183 μM, HER-2=0.197 μM, VEGFR-2=0.235 μM). Multi-target kinase-IN-7 is promising for research of solid tumors (e.g., lung, breast, prostate cancer)[1].
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Multi-target kinase-IN-7 | Multi-target kinase-IN-7 (Compound 1e) is an orally active multi-target kinase inhibitor (IC50 values: CDK2=0.314 μM, EGFR=0.183 μM, HER-2=0.197 μM, VEGFR-2=0.235 μM). Multi-target kinase-IN-7 is promising for research of solid tumors (e.g., lung, breast, prostate cancer). | |||||||||||||||||||||
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