3018963-27-1
3018963-27-1
Chemical Structure
α-Glucosidase-IN-43
- CAS No.: 3018963-27-1
- Formula:C27H31N3O4
- Molecular Weight:461.55
InChIKey: PIIYDTAOOHVNAQ-UHFFFAOYSA-N
SMILES: O=C1C=C(OCCCCCN2N=NC(COC3=CC(C(C)C)=CC=C3C)=C2)C4=C(O1)C=CC=C4
Biological Activity: α-Glucosidase-IN-43 (compound AS14) is an α-glucosidase inhibitor (IC50: 4.32 μM) with acute hypoglycemic activity. α-Glucosidase-IN-43 exhibits safety and in vivo efficacy, is nontoxic to normal mouse fibroblasts, and is able to rescue streptozotocin (HY-13753)-induced diabetic rats. α-Glucosidase-IN-43 can be used to study postprandial hyperglycemia in diabetic patients[1].
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α-Glucosidase-IN-43 | α-Glucosidase-IN-43 (compound AS14) is an α-glucosidase inhibitor (IC50: 4.32 μM) with acute hypoglycemic activity. α-Glucosidase-IN-43 exhibits safety and in vivo efficacy, is nontoxic to normal mouse fibroblasts, and is able to rescue streptozotocin (HY-13753)-induced diabetic rats. α-Glucosidase-IN-43 can be used to study postprandial hyperglycemia in diabetic patients. | |||||||||||||||||||||
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