30211-77-9
30211-77-9
Chemical Structure
2-Nitro-5-thiocyanatobenzoic acid
Synonym(s): NTCB
- CAS No.: 30211-77-9
- Formula:C8H4N2O4S
- Molecular Weight:224.20
IUPAC Name: 2-nitro-5-thiocyanatobenzoic acid
InChIKey: NQUNIMFHIWQQGJ-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC(SC#N)=CC=C1[N+]([O-])=O
Biological Activity: 2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a highly reactive reagent that transfers its cyano group rapidly to a nucleophilic thiolate. 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2-Nitro-5-thiocyanatobenzoic acid | 99.9% | 2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a highly reactive reagent that transfers its cyano group rapidly to a nucleophilic thiolate. 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives. | ||||||||||||||||||||
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References
- [1]. Qiao Y, et al. Site-Specific Conversion of Cysteine in a Protein to Dehydroalanine Using 2-Nitro-5-thiocyanatobenzoic Acid. Molecules. 2021;26(9):2619. Published 2021 Apr 29. [Content Brief]
- [2]. Price NC. Alternative products in the reaction of 2-nitro-5-thiocyanatobenzoic acid with thiol groups. Biochem J. 1976;159(1):177-180. [Content Brief]
