3022872-60-9
3022872-60-9
Chemical Structure
Tubulin polymerization-IN-93
- CAS No.: 3022872-60-9
- Formula:C22H23NO6
- Molecular Weight:397.42
InChIKey: VZLFTDHICHNNEL-UHFFFAOYSA-N
SMILES: COC1=CC(N(C(C2=CC=CO2)=O)CC3=CC=C(OC)C=C3)=CC(OC)=C1OC
Biological Activity: Tubulin polymerization-IN-93 is a β-tubulin polymerization inhibitor. Tubulin polymerization-IN-93 disrupts the microtubule network structure. Tubulin polymerization-IN-93 activates the spindle assembly checkpoint and promotes Mitotic catastrophe. Tubulin polymerization-IN-93 activates the mitochondrial Apoptotic pathway. Tubulin polymerization-IN-93 exhibits anticancer activity against acute myeloid leukemia[1].
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Tubulin polymerization-IN-93 | Tubulin polymerization-IN-93 is a β-tubulin polymerization inhibitor. Tubulin polymerization-IN-93 disrupts the microtubule network structure. Tubulin polymerization-IN-93 activates the spindle assembly checkpoint and promotes Mitotic catastrophe. Tubulin polymerization-IN-93 activates the mitochondrial Apoptotic pathway. Tubulin polymerization-IN-93 exhibits anticancer activity against acute myeloid leukemia. | |||||||||||||||||||||
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