3024298-12-9
Chemical Structure
Gen 2-Iridium PEG4-C6H12Cl hexafluorophosphate
- CAS No.: 3024298-12-9
- Formula:C52H52ClF16IrN5O5P
- Molecular Weight:1389.62
InChIKey: WPUVRSZCTGALKD-UHFFFAOYSA-N
SMILES: FC(F)(C1=CC=C2[N]([Ir+3]([C-]3=CC(F)=C4)([C-]5=CC(F)=CC(F)=C52)([N](C6=C7)=CC=C7CCC(NCCOCCOCCOCCOCCCCCCCl)=O)([N](C6=C8)=CC=C8C)[N]9=CC(C(F)(F)F)=CC=C9C3=C4F)=C1)F.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
Biological Activity: Gen 2-Iridium PEG4-C6H12Cl hexafluorophosphate is a cell-permeable iridium photocatalyst. Gen 2-Iridium PEG4-C6H12Cl hexafluorophosphate bears a PEG4-hexyl chloride ligand that enables covalent alkylation-based attachment to HaloTag[1][2].
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Gen 2-Iridium PEG4-C6H12Cl hexafluorophosphate | Gen 2-Iridium PEG4-C6H12Cl hexafluorophosphate is a cell-permeable iridium photocatalyst. Gen 2-Iridium PEG4-C6H12Cl hexafluorophosphate bears a PEG4-hexyl chloride ligand that enables covalent alkylation-based attachment to HaloTag. | |||||||||||||||||||||
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References
- [1]. Pan CR, et al. µMap proximity labeling in living cells reveals stress granule disassembly mechanisms. Nat Chem Biol. 2025;21(4):490-500. [Content Brief]
- [2]. AUSTIN J, et al. Intracellular ligation of photocatalysts for photo‑responsive, probe‑mediated protein labeling: WO2023245020A1. 2023‑12‑21.