3025787-76-9
3025787-76-9
Chemical Structure
Val-Ala-PAB-SN38
- CAS No.: 3025787-76-9
- Formula:C38H41N5O9
- Molecular Weight:711.76
InChIKey: RUIIKOODLMEDGD-PAOBLYARSA-N
SMILES: O=C1N2C(C(C(C2)=C(C3=C4)CC)=NC3=CC=C4O)=CC5=C1COC([C@@]5(CC)OC(OCC6=CC=C(C=C6)NC([C@H](C)NC([C@@H](N)C(C)C)=O)=O)=O)=O
Biological Activity: Val-Ala-PAB-SN38 is a drug-linker conjugate for ADC, composed of ADC linker Val-Ala-PAB (HY-125933) and SN38 (HY-13704), which is the active metabolite of the Topoisomerase I inhibitor Irinotecan (HY-16562)[1].
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Val-Ala-PAB-SN38 | Val-Ala-PAB-SN38 is a drug-linker conjugate for ADC, composed of ADC linker Val-Ala-PAB (HY-125933) and SN38 (HY-13704), which is the active metabolite of the Topoisomerase I inhibitor Irinotecan (HY-16562). | |||||||||||||||||||||
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