3026420-43-6

PROTAC BRD4 Degrader-14 Chemical Structure
3026420-43-6

Chemical Structure

PROTAC BRD4 Degrader-14

  • CAS No.: 3026420-43-6
  • Formula:C57H61F2N9O11S2
  • Molecular Weight:1150.27

IUPAC Name: 4-(3,5-difluoropyridin-2-yl)-N-(2-(3-hydroxy-5-(2-(2-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)ethyl)phenoxy)ethyl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxamide

InChIKey: JQHNOZDZLLPAJF-RVLLIKLQSA-N

SMILES: O[C@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)CN1C([C@@H](NC(COCCC4=CC(OCCNC(C5=CC(N(C6=NC=C(F)C=C6F)CC7=CNC8=C7C9=CN(C)C8=O)=C9C=C5CS(=O)(C)=O)=O)=CC(O)=C4)=O)C(C)(C)C)=O

Biological Activity: PROTAC BRD4 Degrader-14 is a PROTAC-type BRD4 degrader, which is predicted to be a weak VHL binder and an inactive BRD4 degrader[1].

Cat. No. Product Name Purity Description Pricing
HY-138637
PROTAC BRD4 Degrader-14 PROTAC BRD4 Degrader-14 is a PROTAC-type BRD4 degrader, which is predicted to be a weak VHL binder and an inactive BRD4 degrader.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References