3027425-38-0
3027425-38-0
Chemical Structure
Aplithianines A
- CAS No.: 3027425-38-0
- Formula:C13H13N7S
- Molecular Weight:299.35
InChIKey: IEDDDZFQZKDRBJ-UHFFFAOYSA-N
SMILES: CN1C=NC=C1C(SCC2)=CN2C3=NC=NC4=C3N=CN4
Biological Activity: Aplithianines A is a potent inhibitor against J-PKAcα with an IC50 of 1 μM , and inhibits wild-type PKA with an IC50 of 84 nM. Aplithianines A inhibits J-PKAcα catalytic activity by competitively binding to the ATP pocket[1].
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Aplithianines A | Aplithianines A is a potent inhibitor against J-PKAcα with an IC50 of 1 μM , and inhibits wild-type PKA with an IC50 of 84 nM. Aplithianines A inhibits J-PKAcα catalytic activity by competitively binding to the ATP pocket. | |||||||||||||||||||||
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