302826-61-5
302826-61-5
Chemical Structure
EPAC 5376753
- CAS No.: 302826-61-5
- Formula:C15H8Cl2N2O3S
- Molecular Weight:367.21
IUPAC Name: 5-((5-(2,4-dichlorophenyl)furan-2-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
InChIKey: QQAOFKJHOUFHKI-UHFFFAOYSA-N
SMILES: O=C(/C(C(N1)=O)=C/C2=CC=C(C3=CC=C(Cl)C=C3Cl)O2)NC1=S
Biological Activity: EPAC 5376753, a 2-Thiobarbituric acid (HY-77962) derivative, is a selective and allosteric Epac inhibitor. EPAC 5376753 inhibits Epac1 with an IC50 of 4 µM in Swiss 3T3 cells. EPAC 5376753 does not inhibit PKA and adenylyl cyclases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EPAC 5376753 | 98.10% | EPAC 5376753, a 2-Thiobarbituric acid (HY-77962) derivative, is a selective and allosteric Epac inhibitor. EPAC 5376753 inhibits Epac1 with an IC50 of 4 µM in Swiss 3T3 cells. EPAC 5376753 does not inhibit PKA and adenylyl cyclases. | ||||||||||||||||||||
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EPAC 5376753 (Standard) | ≥98% | EPAC 5376753 (Standard) is the analytical standard of EPAC 5376753 (HY-111446). This product is intended for research and analytical applications. EPAC 5376753, a 2-Thiobarbituric acid (HY-77962) derivative, is a selective and allosteric Epac inhibitor. EPAC 5376753 inhibits Epac1 with an IC50 of 4 µM in Swiss 3T3 cells. EPAC 5376753 does not inhibit PKA and adenylyl cyclases. | ||||||||||||||||||||
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