3028398-90-2
Chemical Structure
TrxR1-IN-3
- CAS No.: 3028398-90-2
- Formula:C36H52N2O6
- Molecular Weight:608.81
InChIKey: UJGMTXLFZSFGKC-ARWFMNDOSA-N
SMILES: COC1=CC(/C=C/C(N2CCN(C(/C=C(C)/CC[C@@]3([H])[C@@](CC[C@@H](O)C4(C)C)(C)[C@]4([H])CCC3=C)=O)CC2)=O)=CC(OC)=C1OC
Biological Activity: TrxR1-IN-3 is a selective TrxR1 inhibitor with an IC50 of 1.19 μM. TrxR1-IN-3 increases intracellular reactive oxygen species (ROS) levels, induces endoplasmic reticulum (ER) stress, and activates Caspase-dependent Apoptosis. TrxR1-IN-3 exhibits anticancer activity against multiple breast cancer subtypes, including triple-negative breast cancer (TNBC). TrxR1-IN-3 can be used in breast cancer-related research[1].
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TrxR1-IN-3 | TrxR1-IN-3 is a selective TrxR1 inhibitor with an IC50 of 1.19 μM. TrxR1-IN-3 increases intracellular reactive oxygen species (ROS) levels, induces endoplasmic reticulum (ER) stress, and activates Caspase-dependent Apoptosis. TrxR1-IN-3 exhibits anticancer activity against multiple breast cancer subtypes, including triple-negative breast cancer (TNBC). TrxR1-IN-3 can be used in breast cancer-related research. | |||||||||||||||||||||
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