3029155-57-2
3029155-57-2
Chemical Structure
GPR6 inverse agonist 2
- CAS No.: 3029155-57-2
- Formula:C27H31F2N7O2
- Molecular Weight:523.58
InChIKey: YNZBAQFKFWGZNM-VWLOTQADSA-N
SMILES: CC(C)(O)[C@@H](O)C1=CC2=NC(N3CCN(CC4=CC=C(F)C=C4F)CC3)=C(C5=CN(CC)N=C5)N=C2C=N1
Biological Activity: GPR6 inverse agonist 2 (Compound 575) is a selective GPR6 inverse agonist, with IC50 values of < 0.1 μM and 1~30 μM against GPR6 and GPR3, respectively. GPR6 inverse agonist 2 exhibits preliminary cardiac safety, with an IC50 of 21.71 μM for hERG. GPR6 inverse agonist 2 can be used in the research of movement disorders such as Parkinson's disease[1].
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GPR6 inverse agonist 2 | GPR6 inverse agonist 2 (Compound 575) is a selective GPR6 inverse agonist, with IC50 values of < 0.1 μM and 1~30 μM against GPR6 and GPR3, respectively. GPR6 inverse agonist 2 exhibits preliminary cardiac safety, with an IC50 of 21.71 μM for hERG. GPR6 inverse agonist 2 can be used in the research of movement disorders such as Parkinson's disease. | |||||||||||||||||||||
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