3029506-23-5
Chemical Structure
PI4KIII beta inhibitor 5
- CAS No.: 3029506-23-5
- Formula:C24H27F2N3O4S2
- Molecular Weight:523.62
InChIKey: MOUQYNRIEHVZNQ-UHFFFAOYSA-N
SMILES: O=S(C1=C(C=CC(C2=C(N=C(S2)NC(CCCCC)=O)C)=C1)OC)(NCC3=C(C=C(C=C3)F)F)=O
Biological Activity: PI4KIII beta inhibitor 5 is a PI4KIIIβ inhibitor with an IC50 of 19 nM. PI4KIII beta inhibitor 5 can induce cancer cell apoptosis (Apoptosis), cell cycle arrest at the G2/M phase, and autophagy (Autophagy) by inhibiting the PI3K/AKT pathway. PI4KIII beta inhibitor 5 has also demonstrated significant antitumor activity in the H446 xenograft model of small cell lung cancer. PI4KIII beta inhibitor 5 can be used for research in the field of cancer therapy[1].
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PI4KIII beta inhibitor 5 | PI4KIII beta inhibitor 5 is a PI4KIIIβ inhibitor with an IC50 of 19 nM. PI4KIII beta inhibitor 5 can induce cancer cell apoptosis (Apoptosis), cell cycle arrest at the G2/M phase, and autophagy (Autophagy) by inhibiting the PI3K/AKT pathway. PI4KIII beta inhibitor 5 has also demonstrated significant antitumor activity in the H446 xenograft model of small cell lung cancer. PI4KIII beta inhibitor 5 can be used for research in the field of cancer therapy. | |||||||||||||||||||||
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