3031053-17-2
3031053-17-2
Chemical Structure
5-HT2A receptor agonist-10
- CAS No.: 3031053-17-2
- Formula:C13H18ClN3O
- Molecular Weight:267.75
SMILES: COC1=CC=C2C=NN(C2=C1)C[C@H]3CCCN3.Cl
Biological Activity: 5-HT2A receptor agonist-10 (Compound (R)-I-121.HCl) is a 5-HT2A receptor agonist, with an IC50 of 2192.39 nM for h5-HT2A and h5-HT1A, respectively. 5-HT2A receptor agonist-10 can be used for the research of psychosis, mental illnesses and CNS disorders[1][2].
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5-HT2A receptor agonist-10 | 5-HT2A receptor agonist-10 (Compound (R)-I-121.HCl) is a 5-HT2A receptor agonist, with an IC50 of 2192.39 nM for h5-HT2A and h5-HT1A, respectively. 5-HT2A receptor agonist-10 can be used for the research of psychosis, mental illnesses and CNS disorders. | |||||||||||||||||||||
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References
- [1]. Sabnis RW, et al. Novel Indoline Derivatives as Serotonergic Psychedelic Agents for Treating Psychosis, Mental Illness and CNS Disorders. ACS Med Chem Lett. 2025 Jan 23;16(2):196-197. [Content Brief]
- [2]. Slassi A, et al. Indazole derivatives as serotonergic agents useful for the treatment of disorders related thereto. WO2024044848A1.
