3031974-57-6
3031974-57-6
Chemical Structure
Zinilisib
Synonym(s): zinilisibum
- CAS No.: 3031974-57-6
- Formula:C26H29F3N4O3
- Molecular Weight:502.53
InChIKey: SGPSVGQQTKICOA-QGZVFWFLSA-N
SMILES: OC(C(C=CC=C1)=C1N[C@@H](C2=C3C(C(N(C(N4CCN(CC4)CC(F)(F)F)=C3)C)=O)=CC(C)=C2)C)=O
Biological Activity: Zinilisib (Zinilisibum) is a PI3K inhibitor. Zinilisib potently inhibits the phosphorylation of AKT in cells expressing mutant PI3KαH1047R and wild-type PI3Kα, with IC50 values of 1-500 nM and 2-15 μM, respectively. Zinilisib can be used in breast cancer-related research[1][2].
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Zinilisib | Zinilisib (Zinilisibum) is a PI3K inhibitor. Zinilisib potently inhibits the phosphorylation of AKT in cells expressing mutant PI3KαH1047R and wild-type PI3Kα, with IC50 values of 1-500 nM and 2-15 μM, respectively. Zinilisib can be used in breast cancer-related research. | |||||||||||||||||||||
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