3032196-65-6
3032196-65-6
Chemical Structure
TEAD-IN-10
- CAS No.: 3032196-65-6
- Formula:C15H14F3NO
- Molecular Weight:281.27
InChIKey: AEOJURJVNCDASZ-ONEGZZNKSA-N
SMILES: O=C(C=C)N(C1)CC1/C=C/C2=CC=C(C(F)(F)F)C=C2
Biological Activity: TEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on TEAD1 (IC50=14 nM), TEAD2 (IC50=179 nM) and TEAD3 (IC50=4 nnM) as a covalent inhibitor. TEAD-IN-10 can be used for cancer research[1].
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TEAD-IN-10 | TEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on TEAD1 (IC50=14 nM), TEAD2 (IC50=179 nM) and TEAD3 (IC50=4 nnM) as a covalent inhibitor. TEAD-IN-10 can be used for cancer research. | |||||||||||||||||||||
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