3032601-92-3
3032601-92-3
Chemical Structure
PROTAC AR-NTD degrader 1
- CAS No.: 3032601-92-3
- Formula:C41H47ClN6O7
- Molecular Weight:771.30
InChIKey: YTDZCZJXTGPJSL-RACIXVTASA-N
SMILES: O=C(N1)CCC(N2C(C3=CC=C(C=C3C2=O)NCCCN4N=NC(CCCCCOC5=CC=C(C(C)(C)C6=CC=C(OC[C@@H](CCl)O)C=C6)C=C5)=C4)=O)C1=O
Biological Activity: PROTAC AR-NTD degrader 1 is a PROTAC degrader that recruits cereblon and targets the N-terminal domain of the androgen receptor (AR-NTD), thereby inducing the degradation of AR-FL and AR-V7 proteins. PROTAC AR-NTD degrader 1 can be used for studies related to androgen receptor degradation and prostate cancer[1].
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PROTAC AR-NTD degrader 1 | PROTAC AR-NTD degrader 1 is a PROTAC degrader that recruits cereblon and targets the N-terminal domain of the androgen receptor (AR-NTD), thereby inducing the degradation of AR-FL and AR-V7 proteins. PROTAC AR-NTD degrader 1 can be used for studies related to androgen receptor degradation and prostate cancer. | |||||||||||||||||||||
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