3032608-72-0
3032608-72-0
Chemical Structure
JLB2-110c
- CAS No.: 3032608-72-0
- Formula:C71H108N28O12
- Molecular Weight:1545.80
InChIKey: ZSSMANYLNGBKPJ-BPFUNGMASA-N
SMILES: CC(N[C@H](C(N[C@H](C(N[C@H](C(NCCCC[C@@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC([C@@H]2CCCN2C([C@H]3CCCN3C1=O)=O)=O)CC4=CNC=N4)=O)CC5=CC=CC=C5)=O)CCCNC(N)=N)=O)CC6=CNC7=C6C=CC=C7)=O)CN)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O
Biological Activity: JLB2-110c activates MCRs receptor (mMC4R EC50 = 0.34 nM) and has a strong in vivo appetite suppressant effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JLB2-110c | JLB2-110c activates MCRs receptor (mMC4R EC50 = 0.34 nM) and has a strong in vivo appetite suppressant effect. | |||||||||||||||||||||
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References
- [1]. Ericson MD, et al. Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]. ACS Pharmacol Transl Sci. 2024 Apr 2;7(4):1114-1125. [Content Brief]
