3032742-74-5
3032742-74-5
Chemical Structure
IRAK4-IN-11
- CAS No.: 3032742-74-5
- Formula:C16H19N7O
- Molecular Weight:325.37
IUPAC Name: 6-methyl-2-((1-methyl-1H-pyrazol-4-yl)amino)-4-((1-methylcyclopropyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one
InChIKey: YBWPAUYJHMYTBP-UHFFFAOYSA-N
SMILES: CN1C=C(C=N1)NC2=NC3=C(C(NC4(CC4)C)=N2)C(N(C=C3)C)=O
Biological Activity: IRAK4-IN-11 (compound 6) is a potent IRAK4 inhibitor with an IC50 of 0.008 µM. IRAK4-IN-11 shows cell pIRAK4 potencies with an IC50 of 0.19 µM[1].
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IRAK4-IN-11 | IRAK4-IN-11 (compound 6) is a potent IRAK4 inhibitor with an IC50 of 0.008 µM. IRAK4-IN-11 shows cell pIRAK4 potencies with an IC50 of 0.19 µM. | |||||||||||||||||||||
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