3032859-14-3
3032859-14-3
Chemical Structure
SPR7
- CAS No.: 3032859-14-3
- Formula:C30H32ClN3O3
- Molecular Weight:518.05
IUPAC Name: (S)-2-(3-(4-chloro-2-methylphenyl)ureido)-N-((S,E)-6-oxo-1-phenylhept-4-en-3-yl)-3-phenylpropanamide
InChIKey: ZCKYSOLDOQXOCO-IEDMVEOCSA-N
SMILES: O=C(C)/C=C/[C@@H](NC([C@@H](NC(NC(C(C)=C1)=CC=C1Cl)=O)CC2=CC=CC=C2)=O)CCC3=CC=CC=C3
Biological Activity: SPR7 (compound 7) is a potent and selective rhodesain inhibitor, with a Ki of 0.51 nM. SPR7 shows antiparasitic activity against T. b. brucei, with an EC50 of 1.65 μM[1].
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SPR7 | SPR7 (compound 7) is a potent and selective rhodesain inhibitor, with a Ki of 0.51 nM. SPR7 shows antiparasitic activity against T. b. brucei, with an EC50 of 1.65 μM. | |||||||||||||||||||||
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