3032920-59-2
3032920-59-2
Chemical Structure
PTPN2/1-IN-3
- CAS No.: 3032920-59-2
- Formula:C14H18FN3O4S
- Molecular Weight:343.37
InChIKey: CVWLNWLJBZNMAZ-UHFFFAOYSA-N
SMILES: FC1=C(N2CC(NS2(=O)=O)=O)C(O)=CC3=C1CCN(CC)CC3
Biological Activity: PTPN2/1-IN-3 (compound 4) is a modified, orally active PTPN2/N1 inhibitor based on ABBV-CLS-484 (HY-145923). PTPN2/1-IN-3 has anti-tumor effects, inhibiting PTPN2 with an IC50 of 9.3 nM and having an oral bioavailability of 93% in mice[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PTPN2/1-IN-3 | 99.89% | PTPN2/1-IN-3 (compound 4) is a modified, orally active PTPN2/N1 inhibitor based on ABBV-CLS-484 (HY-145923). PTPN2/1-IN-3 has anti-tumor effects, inhibiting PTPN2 with an IC50 of 9.3 nM and having an oral bioavailability of 93% in mice. | ||||||||||||||||||||
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