3033069-84-7
3033069-84-7
Chemical Structure
PI3K/AKT-IN-1
- CAS No.: 3033069-84-7
- Formula:C23H23N5O4S
- Molecular Weight:465.52
IUPAC Name: (E)-4-(4-methoxyphenyl)-2-(methylthio)-6-(2-(3,4,5-trimethoxybenzylidene)hydrazinyl)pyrimidine-5-carbonitrile
InChIKey: WGUUTVSZGSTNKU-DHRITJCHSA-N
SMILES: N#CC1=C(N/N=C/C2=CC(OC)=C(OC)C(OC)=C2)N=C(SC)N=C1C3=CC=C(OC)C=C3
Biological Activity: PI3K/AKT-IN-1 is an effective PI3K/AKT dual inhibitor (IC50 of 6.99, 4.01 and 3.36 μM for PI3Kγ, PI3Kδ and AKT, respectively). PI3K/AKT-IN-1 has anticancer activity and acts by inhibiting PI3K/AKT axis and inducing caspase 3 dependent apoptosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PI3K/AKT-IN-1 | 99.64% | PI3K/AKT-IN-1 is an effective PI3K/AKT dual inhibitor (IC50 of 6.99, 4.01 and 3.36 μM for PI3Kγ, PI3Kδ and AKT, respectively). PI3K/AKT-IN-1 has anticancer activity and acts by inhibiting PI3K/AKT axis and inducing caspase 3 dependent apoptosis. | ||||||||||||||||||||
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