3033084-05-5
3033084-05-5
Chemical Structure
PROTAC FLT3/CDK9 degrader-1
- CAS No.: 3033084-05-5
- Formula:C47H61N13O7
- Molecular Weight:920.07
IUPAC Name: 4-bromoquinoline-6,7-diol
InChIKey: HRLVVEPQLHOYNQ-UHFFFAOYSA-N
SMILES: NC(CC1)CCC1NC2=NC(NC(C=C3)=CC=C3N(CC4)CCN4CCOCCOCCNC(CNC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=O)=C8C(N(C9CCCC9)C=N8)=N2
Biological Activity: PROTAC FLT3/CDK9 degrader-1 is a potent FLT3 and CDK9 dual PROTAC degrader. PROTAC FLT3/CDK9 degrader-1 induces apoptosis and effective degradation of target proteins FLT3 and CDK9. PROTAC FLT3/CDK9 degrader-1 has the potential for the research of FLT3-ITD mutated AML[1].
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PROTAC FLT3/CDK9 degrader-1 | PROTAC FLT3/CDK9 degrader-1 is a potent FLT3 and CDK9 dual PROTAC degrader. PROTAC FLT3/CDK9 degrader-1 induces apoptosis and effective degradation of target proteins FLT3 and CDK9. PROTAC FLT3/CDK9 degrader-1 has the potential for the research of FLT3-ITD mutated AML. | |||||||||||||||||||||
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