3033417-22-7
3033417-22-7
Chemical Structure
HDAC10-IN-2
- CAS No.: 3033417-22-7
- Formula:C19H22N2O2
- Molecular Weight:310.39
IUPAC Name: ethyl 8-bromo-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate
InChIKey: SRFTXZNZUQKTSF-CMDGGOBGSA-N
SMILES: O=C(NO)/C=C/C1CCN(CC1)CC2=CC=CC3=C2C=CC=C3
Biological Activity: HDAC10-IN-2 (compound 10c) is a potent and highly selective HDAC10 inhibitor, with an IC50 of 20 nM. HDAC10-IN-2 modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells[1].
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HDAC10-IN-2 | HDAC10-IN-2 (compound 10c) is a potent and highly selective HDAC10 inhibitor, with an IC50 of 20 nM. HDAC10-IN-2 modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells. | |||||||||||||||||||||
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