3033417-31-8
3033417-31-8
Chemical Structure
HDAC10-IN-1
- CAS No.: 3033417-31-8
- Formula:C18H23N3O2
- Molecular Weight:313.39
IUPAC Name: methyl (S)-2-amino-2-(5-isopropoxypyridin-2-yl)propanoate
InChIKey: SPYVWCZEYVBQGX-VOTSOKGWSA-N
SMILES: CN1C=C(C2=C1C=CC=C2)CN3CCC(CC3)/C=C/C(NO)=O
Biological Activity: HDAC10-IN-1 (compound 13b) is a potent and highly selective HDAC10 inhibitor, with an IC50 of 58 nM. HDAC10-IN-1 modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells[1].
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HDAC10-IN-1 | HDAC10-IN-1 (compound 13b) is a potent and highly selective HDAC10 inhibitor, with an IC50 of 58 nM. HDAC10-IN-1 modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells. | |||||||||||||||||||||
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