3033533-25-1
3033533-25-1
Chemical Structure
SpiD3
- CAS No.: 3033533-25-1
- Formula:C27H22N2O6
- Molecular Weight:470.47
InChIKey: MAJYGNYMOANPNU-UHFFFAOYSA-N
SMILES: O=C1OC2(CC1=C)C(N(CCCN3C(C4(C5=C3C=CC=C5)OC(C(C4)=C)=O)=O)C6=C2C=CC=C6)=O
Biological Activity: SpiD3, a spirocyclic dimer, is an anticancer agent. SpiD3 markedly inhibits malignant B-cell proliferation and suppressed NF-κB activation independent of TME-associated stimuli. SpiD3 induces apoptosis and inhibits protein synthesis in chronic lymphocytic leukemia cells. SpiD3 can be used for study of chronic lymphocytic leukemia (CLL)[1].
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SpiD3 | 98.24% | SpiD3, a spirocyclic dimer, is an anticancer agent. SpiD3 markedly inhibits malignant B-cell proliferation and suppressed NF-κB activation independent of TME-associated stimuli. SpiD3 induces apoptosis and inhibits protein synthesis in chronic lymphocytic leukemia cells. SpiD3 can be used for study of chronic lymphocytic leukemia (CLL). | ||||||||||||||||||||
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