3033701-29-7
3033701-29-7
Chemical Structure
KRAS G12D inhibitor 24
- CAS No.: 3033701-29-7
- Formula:C34H33F3N6O2
- Molecular Weight:614.66
InChIKey: TXSGYODOAZBXEM-PDHRFWIKSA-N
SMILES: OC1=CC(C2=C(F)C3=NC(OC[C@]4(C)CN(C)CC/C4=C\F)=NC(N5C[C@H](N6)CC[C@H]6C5)=C3C=N2)=C7C(C#C)=C(F)C=CC7=C1
Biological Activity: KRAS G12D inhibitor 24 (compound 103) is a potent inhibitor of KRAS G12D, with the IC50 of 0.004 μM. KRAS G12D inhibitor 24 has oral bioactivity[1].
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KRAS G12D inhibitor 24 | KRAS G12D inhibitor 24 (compound 103) is a potent inhibitor of KRAS G12D, with the IC50 of 0.004 μM. KRAS G12D inhibitor 24 has oral bioactivity. | |||||||||||||||||||||
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