3033741-74-8
3033741-74-8
Chemical Structure
STAT6-IN-14
- CAS No.: 3033741-74-8
- Formula:C29H24F4N6O3
- Molecular Weight:580.53
InChIKey: YSRUUVQGRKTXPJ-UHFFFAOYSA-N
SMILES: O=C(C1=CC(NC(C2=CC(C(F)(F)F)=CC3=C2N(CC)C(C4=CC=C(N5C(N(C)N=C5C)=O)C=C4)=C3)=O)=CC=C1F)N
Biological Activity: STAT6-IN-14 is a STAT6 inhibitor that blocks the binding of STAT6-pIL-4Rα, with an IC50 of 1.20 μM. STAT6-IN-14 can inhibit IL-4-induced STAT6 transcriptional activity in STAT6-HEK293 cells. STAT6-IN-14 can be used for research on allergic diseases and inflammation[1].
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STAT6-IN-14 | STAT6-IN-14 is a STAT6 inhibitor that blocks the binding of STAT6-pIL-4Rα, with an IC50 of 1.20 μM. STAT6-IN-14 can inhibit IL-4-induced STAT6 transcriptional activity in STAT6-HEK293 cells. STAT6-IN-14 can be used for research on allergic diseases and inflammation. | |||||||||||||||||||||
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