3034210-97-1
3034210-97-1
Chemical Structure
CDK7-IN-20
- CAS No.: 3034210-97-1
- Formula:C30H26N6O3
- Molecular Weight:518.57
IUPAC Name: (S)-4-acrylamido-N-(5-(5-((2-hydroxy-2-phenylethyl)amino)pyridin-3-yl)-1H-indazol-3-yl)benzamide
InChIKey: VSTRBHWJZOVRDC-HHHXNRCGSA-N
SMILES: C=CC(NC1=CC=C(C=C1)C(NC2=NNC3=C2C=C(C=C3)C4=CC(NC[C@H](C5=CC=CC=C5)O)=CN=C4)=O)=O
Biological Activity: CDK7-IN-20 is a potent, selective and irreversible CDK7 (CDK) inhibitor with an IC50 value of 4 nM. CDK7-IN-20 displays >206-fold selectivity for CDK7 over CDK1, CDK2, CDK3, CDK5, CDK6, CDK9 and CDK12 . CDK7-IN-20 has the potential for autosomal dominant polycystic kidney disease (ADPKD) research[1].
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CDK7-IN-20 | CDK7-IN-20 is a potent, selective and irreversible CDK7 (CDK) inhibitor with an IC50 value of 4 nM. CDK7-IN-20 displays >206-fold selectivity for CDK7 over CDK1, CDK2, CDK3, CDK5, CDK6, CDK9 and CDK12 . CDK7-IN-20 has the potential for autosomal dominant polycystic kidney disease (ADPKD) research. | |||||||||||||||||||||
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