3034542-28-1
3034542-28-1
Chemical Structure
KIF18A-IN-10
- CAS No.: 3034542-28-1
- Formula:C26H30F2N6O4S
- Molecular Weight:560.62
InChIKey: JKYUWOONBCWYMP-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(NS(CCO)(=O)=O)C=C1N2CCC3(CC3)CC2)NC4=NC5=C(C=NN5C6CC(F)(F)C6)C=C4
Biological Activity: KIF18A-IN-10 (Compound 24) is a potent KIF18A inhibitor, with an IC50 value of 23.8 nM. KIF18A-IN-10 has anticancer activity, with IC50 values of less than 100 nM in OVCAR3 and MDA-MB-157 cells[1].
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KIF18A-IN-10 | KIF18A-IN-10 (Compound 24) is a potent KIF18A inhibitor, with an IC50 value of 23.8 nM. KIF18A-IN-10 has anticancer activity, with IC50 values of less than 100 nM in OVCAR3 and MDA-MB-157 cells. | |||||||||||||||||||||
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