3034593-10-4
3034593-10-4
Chemical Structure
GluN2B-NMDAR antagonist-2
- CAS No.: 3034593-10-4
- Formula:C24H25Cl2N3O3
- Molecular Weight:474.38
InChIKey: LBSFKARCSBQZBA-BOXHHOBZSA-N
SMILES: O=C(C1=CC=CC=C12)O[C@H]2CCCN(CC3)CCN3C(C4=CC(C=CC=C5Cl)=C5N4)=O.Cl
Biological Activity: GluN2B-NMDAR antagonist-2 (compound S-58) is a potent, selective and cross the blood-brain barrier NMDAR-GluN2B antagonist with an IC50 value of 74.01, nM. GluN2B-NMDAR antagonist-2 shows mild cytotoxicity. GluN2B-NMDAR antagonist-2 decreases the cerebral infarction rates and neurologic deficit scores. GluN2B-NMDAR antagonist-2 has the potential for the research of stroke[1].
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GluN2B-NMDAR antagonist-2 | GluN2B-NMDAR antagonist-2 (compound S-58) is a potent, selective and cross the blood-brain barrier NMDAR-GluN2B antagonist with an IC50 value of 74.01, nM. GluN2B-NMDAR antagonist-2 shows mild cytotoxicity. GluN2B-NMDAR antagonist-2 decreases the cerebral infarction rates and neurologic deficit scores. GluN2B-NMDAR antagonist-2 has the potential for the research of stroke. | |||||||||||||||||||||
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