3034896-75-5
Chemical Structure
Tubulin/MMP-IN-1
- CAS No.: 3034896-75-5
- Formula:C38H44NO9P
- Molecular Weight:689.73
IUPAC Name: 4-((3-(naphthalen-2-yl)-3-oxopropyl)amino)benzenesulfonamide
InChIKey: KYWNCKLZETWRBX-PFONDFGASA-N
SMILES: CCOP(OCC)(C(C1=CC=CC=C1C)NC2=CC=C(C=C2)CC(OC3=CC(/C=C\C4=CC(OC)=C(C(OC)=C4)OC)=CC=C3OC)=O)=O
Biological Activity: Tubulin/MMP-IN-1 (compound 15g) is a potent inhibitor of tubulin and MMP. Tubulin/MMP-IN-1 has the potential for the research of cancer diseases. Tubulin/MMP-IN-1 suppresses tubulin polymerization, induces cell cycle arrest at the G2/M phase, leads to reactive oxidative stress (ROS) generation of HepG2 cells, and results in apoptosis by the mitochondrial-dependent apoptotic pathway[1].
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Tubulin/MMP-IN-1 | Tubulin/MMP-IN-1 (compound 15g) is a potent inhibitor of tubulin and MMP. Tubulin/MMP-IN-1 has the potential for the research of cancer diseases. Tubulin/MMP-IN-1 suppresses tubulin polymerization, induces cell cycle arrest at the G2/M phase, leads to reactive oxidative stress (ROS) generation of HepG2 cells, and results in apoptosis by the mitochondrial-dependent apoptotic pathway. | |||||||||||||||||||||
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