3036050-96-8
3036050-96-8
Chemical Structure
Anti-osteoporosis agent-8
- CAS No.: 3036050-96-8
- Formula:C18H19F3N2O2Se
- Molecular Weight:431.31
InChIKey: HJNMJWDQWGLWOA-HNNXBMFYSA-N
SMILES: O=C(NC1=CC=NC=C1)C([Se]C2=CC=CC=C2)C(C)(OCC(F)(F)F)C
Biological Activity: Anti-osteoporosis agent-8 (Compound 4aa) is an inhibitor for RANKL, which inhibits RANKL-induced osteoclastogenesis and osteoclast differentiation (IC50 is 2.41 μM) in cells RAW264.7. Anti-osteoporosis agent-8 ameliorates bone loss in an ovariectomized (OVX) mice model[1].
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Anti-osteoporosis agent-8 | Anti-osteoporosis agent-8 (Compound 4aa) is an inhibitor for RANKL, which inhibits RANKL-induced osteoclastogenesis and osteoclast differentiation (IC50 is 2.41 μM) in cells RAW264.7. Anti-osteoporosis agent-8 ameliorates bone loss in an ovariectomized (OVX) mice model. | |||||||||||||||||||||
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