3037516-91-6
3037516-91-6
Chemical Structure
CXCR2 antagonist 4
- CAS No.: 3037516-91-6
- Formula:C15H14F2N4OS2
- Molecular Weight:368.42
IUPAC Name: 1-(3-methoxybenzyl)-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrrolo[3,2-c]quinolin-4-amine
InChIKey: UDCSAFOSROJLQM-MRVPVSSYSA-N
SMILES: OC[C@@H](C)NC1=C2SC=NC2=NC(SCC3=CC=CC(F)=C3F)=N1
Biological Activity: CXCR2 antagonist 4 (compound 7) is a potent CXCR2 antagonist with an IC50 value of 0.13 μM. CXCR2 antagonist 4 can inhibit CXCL8-induced cytosolic calcium increase (IC50 = 27 μM). CXCR2 antagonist 4 can be used for researching anticancer[1].
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CXCR2 antagonist 4 | CXCR2 antagonist 4 (compound 7) is a potent CXCR2 antagonist with an IC50 value of 0.13 μM. CXCR2 antagonist 4 can inhibit CXCL8-induced cytosolic calcium increase (IC50 = 27 μM). CXCR2 antagonist 4 can be used for researching anticancer. | |||||||||||||||||||||
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