3037517-09-9
3037517-09-9
Chemical Structure
CXCR2 antagonist 5
- CAS No.: 3037517-09-9
- Formula:C15H14F2N4O2S
- Molecular Weight:352.36
IUPAC Name: 5-(2-bromophenyl)-1-(3-(5-(2-chlorophenyl)-2H-tetrazol-2-yl)propyl)-7-fluoro-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
InChIKey: ZLRWWDGGLOPBOT-MRVPVSSYSA-N
SMILES: C[C@@H](NC1=C2C=NOC2=NC(SCC3=CC=CC(F)=C3F)=N1)CO
Biological Activity: CXCR2 antagonist 5 (compound 25) is a potent CXCR2 antagonist. CXCR2 antagonist 5 shows potent CXCR2 binding affinity (IC50=0.013 µM) and calcium mobilization (IC50=0.1 µM)[ 1].
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CXCR2 antagonist 5 | CXCR2 antagonist 5 (compound 25) is a potent CXCR2 antagonist. CXCR2 antagonist 5 shows potent CXCR2 binding affinity (IC50=0.013 µM) and calcium mobilization (IC50=0.1 µM)[ 1]. | |||||||||||||||||||||
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