3037604-86-4
3037604-86-4
Chemical Structure
BLM-IN-2
- CAS No.: 3037604-86-4
- Formula:C33H38BrFN4O
- Molecular Weight:605.58
IUPAC Name: (E)-3-(4-bromobenzyl)-7-((3-(diethylamino)propyl)amino)-6-fluoro-2-(4-isopropylstyryl)quinazolin-4(3H)-one
InChIKey: ZTSBFUZGEKUIED-SFQUDFHCSA-N
SMILES: CCN(CCCNC1=C(C=C2C(N(C(/C=C/C3=CC=C(C=C3)C(C)C)=NC2=C1)CC4=CC=C(C=C4)Br)=O)F)CC
Biological Activity: BLM-IN-2 is a Bloom's Syndrome Protein (BLM) inhibitor with an IC50 value of 0.8 μM. BLM-IN-2 effectively suppresses the proliferation, invasion, cell cycle arrest and apoptosis of CRC cells. BLM-IN-2 can be used for the reserarch of colorectal cancer (CRC)[1].
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BLM-IN-2 | BLM-IN-2 is a Bloom's Syndrome Protein (BLM) inhibitor with an IC50 value of 0.8 μM. BLM-IN-2 effectively suppresses the proliferation, invasion, cell cycle arrest and apoptosis of CRC cells. BLM-IN-2 can be used for the reserarch of colorectal cancer (CRC). | |||||||||||||||||||||
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