3037777-07-1
3037777-07-1
Chemical Structure
Di(MMY-SJG)-Ph-prop-2-yne-1-sulfonic acid
- CAS No.: 3037777-07-1
- Formula:C39H36N4O9S
- Molecular Weight:736.79
InChIKey: VIRSRYACYGZFBR-VMPREFPWSA-N
SMILES: O=C1C2=CC(OC)=C(OCC3=CC(COC4=C(C=C5C(N=C[C@@]6([H])N(CC(C6)=C)C5=O)=C4)OC)=CC(C#CCS(=O)(O)=O)=C3)C=C2N=C[C@@]7([H])N1CC(C7)=C
Biological Activity: Di(MMY-SJG)-Ph-prop-2-yne-1-sulfonic acid (Compound 5) is a cytotoxic pyrrolobenzodiazepine (PBD) dimer derivative. Di(MMY-SJG)-Ph-prop-2-yne-1-sulfonic acid exhibits moderate DNA alkylating activity. Di(MMY-SJG)-Ph-prop-2-yne-1-sulfonic acid can be used as the payload of ADC, thereby demonstrating strong antigen-dependent cytotoxicity[1].
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Di(MMY-SJG)-Ph-prop-2-yne-1-sulfonic acid | Di(MMY-SJG)-Ph-prop-2-yne-1-sulfonic acid (Compound 5) is a cytotoxic pyrrolobenzodiazepine (PBD) dimer derivative. Di(MMY-SJG)-Ph-prop-2-yne-1-sulfonic acid exhibits moderate DNA alkylating activity. Di(MMY-SJG)-Ph-prop-2-yne-1-sulfonic acid can be used as the payload of ADC, thereby demonstrating strong antigen-dependent cytotoxicity. | |||||||||||||||||||||
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