3038178-85-4
3038178-85-4
Chemical Structure
PI3Kδ-IN-20
- CAS No.: 3038178-85-4
- Formula:C20H17ClN8
- Molecular Weight:404.86
InChIKey: GXOALVFPYNWGHO-LBPRGKRZSA-N
SMILES: CC1=NN([C@H](C2=NN(C3=CC(Cl)=CC=C23)C4=CC=NC=C4)C)C5=C1C(N)=NC=N5
Biological Activity: PI3Kδ-IN-20 (compound (S)-36) is a potent inhibitor of PI3Kδ, with the IC50 of 6.4 nM. PI3Kδ-IN-20 has oral bioactivity. PI3Kδ-IN-20 shows significant suppression of cell proliferation and remarkable induction of apoptosis both in vitro and in vivo[1].
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PI3Kδ-IN-20 | PI3Kδ-IN-20 (compound (S)-36) is a potent inhibitor of PI3Kδ, with the IC50 of 6.4 nM. PI3Kδ-IN-20 has oral bioactivity. PI3Kδ-IN-20 shows significant suppression of cell proliferation and remarkable induction of apoptosis both in vitro and in vivo. | |||||||||||||||||||||
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