3040385-73-4
3040385-73-4
Chemical Structure
Tubulin polymerization-IN-63
- CAS No.: 3040385-73-4
- Formula:C20H24ClCuN5O2S
- Molecular Weight:497.50
InChIKey: IRXHNANMLCLESW-VNFMCAGGSA-L
SMILES: Cl[Cu]12([N]3(C4)CCOCC3)[N](N=C(NC5=CC(C)=C(O)C(C)=C5)S2)=CC6=CC=CC4=[N]61
Biological Activity: Tubulin polymerization-IN-63 (compound 6) is a tubulin polymerization inhibitor. The IC50 value of Tubulin polymerization-IN-63 for MES-SA cells is 0.29 μM. Tubulin polymerization-IN-63 can be used in cancer research[1].
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Tubulin polymerization-IN-63 | Tubulin polymerization-IN-63 (compound 6) is a tubulin polymerization inhibitor. The IC50 value of Tubulin polymerization-IN-63 for MES-SA cells is 0.29 μM. Tubulin polymerization-IN-63 can be used in cancer research. | |||||||||||||||||||||
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References
- [1]. Milunovic MNM, et al. Copper(II) Complexes with Isomeric Morpholine-Substituted 2-Formylpyridine Thiosemicarbazone Hybrids as Potential Anticancer Drugs Inhibiting Both Ribonucleotide Reductase and Tubulin Polymerization: The Morpholine Position Matters. J Med Chem. 2024 Jun 13;67(11):9069-9090. [Content Brief]
